Bioinformatics Research Scientist (Bioinformatician II)
Company: Benaroya Research Institute
Posted on: May 14, 2022
Overview:This highly collaborative 2+ year position provides a
unique opportunity for multi-disciplinary research spanning Systems
Immunology and the Human Immunophenotyping (HIP) Core/Long Lab,
under the guidance of Dr. Hamid Bolouri and Dr. Alice Long.
The HIP Core and Long Lab are translational immunology labs that
study autoimmunity by using cytometry-based assays on samples from
clinical trials paired with selected samples to better understand
mechanisms of disease.
The Bolouri Lab is focused on developing and applying computational
systems immunology methods to better understand immune
dysregulation in autoimmunity, cancer, and infection.
We are seeking a bioinformatics scholar with strong interests in
high-dimensional flow and mass cytometry, omics technologies, and
systems immunology, as well as deep expertise in the development
and application of bioinformatics methods and tools to emerging
challenges in immunology research. Together, we hope to foster
creative thinking that will move the field closer to treatments of
immune mediated diseases.
- Perform cytometry data annotation, curation, and harmonization
- Work independently and collaboratively with Long lab and HIP
Core researchers to design, implement, and analyze new
- Evaluate emerging computational methods and tools for cytometry
data processing and analysis. Recommend, adapt, and implement
best-of-class data processing/analysis pipelines for large-scale
application at BRI.
- Develop, adapt, extend, and implement best-of-class methods (i)
to integrate cytometry data from multiple batches and projects,
(ii) to integrate cytometry data from different platforms, (iii)
integrate cytometry data with other data sets such as
bulk/single-cell RNA-seq, ATAC-seq, and proteomics.
- Educate HIP Core and Long lab scientists in bioinformatics,
biostatistics, and computational best practices.
- Attend and present data at external scientific meetings and
conferences as appropriate.
- Facilitate best visualization of data as appropriate and
- Set and meet deadlines and milestones.
- Be forward thinking by welcoming opportunities for additional
training and engagement with the larger scientific community.
- Foster a friendly, collaborative learning environment that
prioritizes integrity and respect, innovation and agility, and
- PhD. in bioinformatics, biostatistics, computational biology,
systems biology/immunology; or in other STEM disciplines with a
strong understanding of the principals of bioinformatics and
high-throughput technologies; alternatively an M.S. in the above
listed fields and 3 or more years professional experience.
- Demonstrated track record of technical proficiency, scientific
creativity, collaboration with others, and independent
- Excellent oral and written communication skills.
- Excellent time management, task organization, and multi-tasking
- Good understanding of molecular biology, genetics, and
- Deep understanding of 'Big Data' and high-dimensional-data
analysis methods (e.g. feature-selection, dimensionality reduction,
pattern recognition, machine learning).
- Proficiency operating in a mixed UNIX-Mac-Windows
- Programming skills in Unix shell scripting languages
- Proficiency in bioinformatics analysis using R/Bioconductor and
- Familiarity with version management, high-performance and cloud
computing environments, job scheduling, batch-processing, and
workflow management systems.We strongly support and encourage
applicants from diverse backgrounds. All qualified applicants will
receive consideration for employment without regard to race, color,
religion, sex, sexual orientation, gender identity, national
origin, citizenship, disability or protected veteran status.
Keywords: Benaroya Research Institute, Seattle , Bioinformatics Research Scientist (Bioinformatician II), Other , Seattle, Washington
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