Senior Scientist Applied Bioinformatics
Company: Bristol Myers Squibb
Location: Seattle
Posted on: August 6, 2022
Job Description:
At Bristol Myers Squibb, we are inspired by a single vision -
transforming patients' lives through science. In oncology,
hematology, immunology and cardiovascular disease - and one of the
most diverse and promising pipelines in the industry - each of our
passionate colleagues contribute to innovations that drive
meaningful change. We bring a human touch to every treatment we
pioneer. Join us and make a difference.We are seeking an innovative
scientist to join our Applied Bioinformatics team in the
Computational Genomics group. This group of computational
scientists is responsible for advancing Bristol-Myers Squibb's
industry-leading pipeline in multiple therapeutic areas (including
Immuno-Oncology, Cardiovascular, Fibrosis, and Immunoscience)
through the strategic application of cutting-edge bioinformatics
approaches. Expertise in contemporary methods for processing,
analysis, integration and visualization of NGS data, including
single cell sequence data, are prerequisite. The position would
suit an individual with exceptional NGS bioinformatics,
computational biology, communication and collaboration skills
focused on development of innovative methods, for the exploration
of new and existing data types.Responsibilities
- Develop and apply leading-edge computational analysis and
biological interpretation approaches aligned with key BMS
scientific objectives and with focus on bulk and single-cell NGS
profiling experiments.
- Integrate data across assay platforms and transfer knowledge to
impact early drug discovery and translational development
programs.
- Apply contemporary methods for genomic data processing,
analysis, interpretation and visualization. Contribute to
development and implementation of both established and novel NGS
data processing protocols.
- Participate in design and analysis of laboratory experiments;
algorithm, platform & vendor performance evaluations; and the
development of novel profiling protocols.
- Author scientific reports, and present methods, results and
conclusions to publishable standard.
- Contribute to planning and execution of collaborative projects
with leading academic and commercial research groups
worldwide.Qualifications:
- Ph.D. in Bioinformatics, Computational Biology or another
relevant field or M.Sc. in one of the same fields and 5+ years of
experience in the field
- Expert knowledge and hands on experience on current
bioinformatics trends, public genomic tools, databases and
utilities, with a focus on Next Generation Sequencing methods.
- Familiarity with NGS processing and analytical pipelines e.g.
alignment, SNV, SV and CNV calling algorithms, common NGS
manipulation and visualization tools and standardized NGS data
formats (e.g. SAM/BAM, VCF).
- Experience with machine learning/deep learning (ML/DL) methods
and their application.
- Experience with single cell assays and contemporary analytical
methods of various single cell modalities (scRNA-seq, scATAC-seq
etc)
- Fluency with Linux-based high-performance computing
environments, AWS cloud computing, reproducible research and code
sharing and tracking practices.
- Excellent programming skills using scripting languages (Python,
R/Bioconductor, Shiny and contemporary database structures), and
expertise in algorithmic implementation, statistical programming
and data manipulation.
- Strong problem-solving and collaboration skills, and rigorous
and creative thinking
- Excellent written and oral communication skills, including an
ability to explain complex ideas to computational scientists,
experimentalists, and cliniciansAround the world, we are passionate
about making an impact on the lives of patients with serious
diseases. Empowered to apply our individual talents and diverse
perspectives in an inclusive culture, our shared values of passion,
innovation, urgency, accountability, inclusion and integrity bring
out the highest potential of each of our colleagues.Bristol Myers
Squibb recognizes the importance of balance and flexibility in our
work environment. We offer a wide variety of competitive benefits,
services and programs that provide our employees with the resources
to pursue their goals, both at work and in their personal
lives.Physical presence at the BMS worksite or physical presence in
the field is an essential job function of this role which the
Company deems critical to collaboration, innovation, productivity,
employee well-being and engagement, and enhances the Company
culture.To protect the safety of our workforce, customers, patients
and communities, the policy of the Company requires all employees
and workers in the U.S. and Puerto Rico to be fully vaccinated
against COVID-19, unless they have received an exception based on
an approved request for a medical or religious reasonable
accommodation. Therefore, all BMS applicants seeking a role located
in the U.S. and Puerto Rico must confirm that they have already
received or are willing to receive the full COVID-19 vaccination by
their start date as a qualification of the role and condition of
employment. This requirement is subject to state and local law
restrictions and may not be applicable to employees working in
certain jurisdictions such as Montana. This requirement is also
subject to discussions with collective bargaining representatives
in the U.S.Our company is committed to ensuring that people with
disabilities can excel through a transparent recruitment process,
reasonable workplace adjustments and ongoing support in their
roles. Applicants can request an approval of accommodation prior to
accepting a job offer. If you require reasonable accommodation in
completing this application or if you are applying to a role based
in the U.S. or Puerto Rico and you believe that you are unable to
receive a COVID-19 vaccine due to a medical condition or sincerely
held religious belief, during or any part of the recruitment
process, please direct your inquiries to
adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility
to access our complete Equal Employment Opportunity statement.Any
data processed in connection with role applications will be treated
in accordance with applicable data privacy policies and
regulations.
Keywords: Bristol Myers Squibb, Seattle , Senior Scientist Applied Bioinformatics, Other , Seattle, Washington
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