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Scientist, CAR-T and TCR-T Biology

Company: Bristol Myers Squibb
Location: Seattle
Posted on: January 26, 2023

Job Description:

Working with UsChallenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: The Immuno-Oncology and Cellular Therapy Thematic Research Center is one of the fundamental research and early development engines delivering therapeutics to patients. - Our mission is to drive leadership in the use of immune effector cell-based therapies in hematological and solid cancers. - More specifically, we are focused on developing engineered cell-based therapies, as well as biotherapeutics, both aimed at harnessing the power of immune cells to mediate anti-tumor activity. The team integrates discovery research seamlessly with preclinical sciences, translational research and early clinical development in collaboration with colleagues across the Research and Development organization. Our thematic focus allows the group to capitalize on the cutting edge science that underpins the action of many of the company's most innovative therapeutics, without being constrained by drug modality or disease indication.The Cell Therapy Preclinical Biology team is seeking a highly motivated and passionate Scientist to help us deliver on this critical goal. The ideal candidate is an experienced research scientist with a strong background in T cell engineering with expertise engineering and optimizing next generation cell therapy candidates. The preferred candidate will have experience developing and implementing -in vitro -functional assays to measure T cell and CAR-T function, including proliferation, cytokine production, phenotypic analysis and cytotoxic activity. -This position is ideal for the innovative scientist who can lead with their data to influence program strategy and direction.Responsibilities include but are not limited to:

  • Design, execution, analysis, and communication of results from engineered T cell functional studies
  • Deliver data packages to lead and influence portfolio project strategic decisions -
  • Independently manage workload and execute bench research activities with minimal supervision, time management to contribute to multiple projects in parallel - -
  • Manage project timelines and deliverables, delivery of time-sensitive decisional data packages, support engagement with departmental and cross-functional stakeholders -
  • Maintain expertise and knowledge of developments in cell therapy field and apply knowledge to overcome technical barriers -
  • Technical resource for junior staff members -
  • Maintain detailed and timely documentation of results in electronic notebook -Basic Qualifications: -
    • Bachelor's Degree
      • 5+ years of academic and / or industry experience -Or
        • Master's Degree -
          • 3+ years of academic and / or industry experience -Or
            • Ph.D. or equivalent advanced degree in the Life Sciences
              • No experience necessarySkillset:
                • Ability to independently plan and execute CAR-T production, assay development, and characterization studies -
                • Expertise in primary T cell engineering, including CAR-T molecular design, viral or nonviral engineering strategies, and CRISPR editing
                • Ability to work productively as a team member and individual contributor -
                • Experience with -in vitro -technologies typically employed to assess T cell functionality including but not limited to MSD, IncuCyte-based assays, multi-parameter flow cytometry for phenotypic characterization of T cells, T cell activation assays, T cell proliferation analysis
                • Strong communication skills for working with cross-functional teams as well cross-departmental colleagues
                • Strong organizational skillset to ensure thorough and timely planning, execution, communication and documentation of experiments#LI-OnsiteThe starting compensation for this job -is a range from $92,000 - $115,000, plus incentive cash and stock opportunities (based on eligibility).The starting pay rate takes into account characteristics of the job, such as required skills and the where the job is performed.Final individual compensation will be decided -based on demonstrated -experience. -For more on benefits, please visit our -.Eligibility for specific benefits listed on our BMS Careers site may vary based on the job and location.Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. -Physical presence at the BMS worksite or physical presence in the field is an essential job function of this role which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and enhances the Company culture.To protect the safety of our workforce, customers, patients and communities, the policy of the Company requires all employees and workers in the U.S. and Puerto Rico to be fully vaccinated against COVID-19, unless they have received an exception based on an approved request for a medical or religious reasonable accommodation. - Therefore, all BMS applicants seeking a role located in the U.S. and Puerto Rico must confirm that they have already received or are willing to receive the full COVID-19 vaccination by their start date as a qualification of the role and condition of employment. - This requirement is subject to state and local law restrictions and may not be applicable to employees working in certain jurisdictions such as Montana. This requirement is also subject to discussions with collective bargaining representatives in the U.S.Our company is committed to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace adjustments and ongoing support in their roles. Applicants can request an approval of accommodation prior to accepting a job offer. If you require reasonable accommodation in completing this application or if you are applying to a role based in the U.S. or Puerto Rico and you believe that you are unable to receive a COVID-19 vaccine due to a medical condition or sincerely held religious belief, during or any part of the recruitment process, please direct your inquiries to . Visitto access our complete Equal Employment Opportunity statement.BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

Keywords: Bristol Myers Squibb, Seattle , Scientist, CAR-T and TCR-T Biology, Other , Seattle, Washington

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