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Senior Research Associate

Company: ASK Staffing, Inc
Location: Seattle
Posted on: May 26, 2023

Job Description:

Job description:

  • The Cell Therapy Product Sciences department is seeking two Senior Research Associate to support the development of gene engineered T cell products.
  • Product Sciences is responsible for developing and executing mechanism of action and characterization studies to support the development of gene-engineered T cell therapies.
  • The primary focus of the Senior Research Associate - Product Sciences role will be to build CAR/TCR T cell product and process understanding in support of early and late-stage CAR T with a particular focus on exploratory/investigational needs for late-stage programs.
  • Successful candidates will have a very strong foundation in cell-based assays (flow cytometry, proliferation, cytotoxicity, cytokine release, etc) and some background in human T cell biology and/or other immune cell types.
  • Experience with implementation and optimization of a broad range of in vitro cell-based and molecular assays is critical (especially multi-color flow cytometry and cell culture).
  • This role is highly collaborative and requires attention to detail, a healthy sense of urgency, a strong desire to learn, and a passion for exploratory and investigational science. Furthermore, a demonstrated ability to support cross-functional teams and independently design and execute studies to meet project goals is very highly desirable (albeit not a requirement and will depend on the applicant's individual qualifications).
  • Primarily, support late-stage drug product and manufacturing process understanding by performing exploratory studies and investigational analyses including experimental design and execution, statistical/correlative analyses of existing data sets, writing technical reports, presenting data, etc. Additionally, depending on the applicant's individual qualifications, duties and responsibilities include the following:
  • Design and deploy in-depth characterization of gene engineered T cells using flow cytometry, genome-wide expression analysis, metabolic profiling, and/or additional cutting-edge analytical techniques.
  • Participate in cross-functional teams to support the development of gene engineered T cell therapeutic platforms.
  • Identification and development of novel analytical approaches for interrogating gene engineered T cell function.
  • Develop and maintain relationships with external collaborators and service providers.
  • Serve as T cell biology subject matter expert in multidisciplinary team setting, that includes non-clinical, clinical, regulatory, and CMC functions.
  • Perform and manage instrument and method troubleshooting
  • Author, review, and approve technical documents, including methods, protocols, reports, and SOPs
  • Learn and apply ICH/FDA/EMEA guidance and current thinking.About ASK: ASK Consulting is an award-winning technology and professional services recruiting firm servicing Fortune 500 organizations nationally. With 5 nationwide offices, two global delivery centers, and employees in 42 states-ASK Consulting connects people with amazing opportunities.ASK Consulting is an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all associates.

Keywords: ASK Staffing, Inc, Seattle , Senior Research Associate, Other , Seattle, Washington

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