Transgenic Animal Core Specialist

Company: Fred Hutchinson Cancer Research Center
Location: Seattle
Posted on: May 28, 2023

Job Description:

Overview
Fred Hutchinson Cancer Center is an independent, nonprofit organization providing adult cancer treatment and groundbreaking research focused on cancer and infectious diseases. Based in Seattle, Fred Hutch is the only National Cancer Institute-designated cancer center in Washington.
With a track record of global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy and COVID-19 vaccines, Fred Hutch has earned a reputation as one of the world's leading cancer, infectious disease and biomedical research centers. Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures to the world's deadliest diseases and make life beyond cancer a reality.
At Fred Hutch we value collaboration, compassion, determination, excellence, innovation, integrity and respect. These values are grounded in and expressed through the principles of diversity, equity and inclusion. Our mission is directly tied to the humanity, dignity and inherent value of each employee, patient, community member and supporter. Our commitment to learning across our differences and similarities make us stronger. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an anti-racist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, anti-racism and inclusion.
Research Technician III (Transgenic Animal Core Specialist) is responsible for conducting technical procedures related to Genetically engineered mouse modeling (GEMM) program within Preclinical modeling core. Transgenic core technician will be responsible for the day-to-day technical operation of the transgenic core facility at Fred Hutch. In consultation with the core Director, the technician will execute all standard protocols essential for generating transgenic mouse lines. This position requires flexibility, good communication skills and an extensive background in technical procedures. -
Responsibilities
Scope of Responsibilities: -
Works independently under the guidance of and in conjunction with the Principal Investigator,---Director---or senior personnel---in---accomplishing the scientific goals of a project. Uses discretion and judgement in performance of duties.------ -
Essential Tasks:

• Be responsible for the daily operation of the GEMM program to meet research goals and achieve results. The specific tasks include Animal husbandry and maintenance, Embryo handling and manipulation, microinjections, sperm cryopreservation and in vitro fertilization. (60%) -
  
• May lead or supervise other laboratory personnel and manage program workflow, schedules and determines priorities to maintain progress on all projects. (10%) -
  
• Participates in hiring and staffing decisions. Leads or assists with training laboratory personnel. (5%) -
  
• Determine the most suitable methods to be used in research; determine appropriate experimental controls. (5%) -
  
• Maintain laboratory notebooks and accurate logs. Record data daily into multiple custom databases, including colony/breeding data, microinjection session data etc. Use software tools like Microsoft Excel, Word, SharePoint etc for data & note gathering, maintenance and sharing. - (10%) -
  
• Support the maintenance of samples and laboratory reagents, stocks, media surgical instruments and maintain laboratory equipment (clippers, pipet holders, scope etc.). Process and store specimen samples, and thaw and prepare frozen samples, if needed for implantation. (10%) - -
  Qualifications
  Required: - -
  

• 
  
• A Bachelor of Sciences degree in a medical, biological or allied field.
  
• 3-4 years of experience in classical transgenic techniques, sperm/embryo cryopreservation and IVF. - -
  
• Experience in performing research using mouse models -
  
• Experience with classical transgenic techniques, pronuclear microinjections, sperm/embryo cryopreservation and IVF - -
  
• Microsurgery experience - -
  
• Demonstrated ability to lead individual performers in delivering services, ability to learn and adapt to new systems and techniques -
  
  Preferred: - -
  
  • 
    
  • AALAS certification
    
  • > 4 years' experience in performing research using mouse models and/or generating mouse models using CRISPR/Cas9 technology -
    
  • Experience in generating mouse models using CRISPR/Cas9 technology -
    
  • Experience in ES cell culture and blastocyst microinjection -
    
  • Proven records of generating transgenic mouse models
    
    Fred Hutchinson Cancer Center has a mandatory COVID-19 vaccine requirement, with exceptions only for approved medical or religious accommodations. As a condition of employment, newly hired employees must, prior to their first day of employment: Provide proof of being fully vaccinated against COVID-19 ; ORInitiate the accommodations process to request a religious or medical accommodation (medical accommodations require a healthcare provider's certification).
    A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and antiracism in your career or that will be made through your work at Fred Hutch is requested of all finalists.
    The annual base salary range for this position is from $65,484 to $96,349 and pay offered will be based on experience and qualifications.------ Relocation and or sign bonus can be offered for qualifying candidates. -
    Fred Hutchinson Cancer Center offers employees a comprehensive benefits package designed to enhance health, well-being, and financial security. Benefits include medical/vision, dental, flexible spending accounts, life, disability, retirement, family life support, employee assistance program, onsite health clinic, tuition reimbursement, paid vacation (12-22 days per year), paid sick leave (12-25 days per year), paid holidays (13 days per year), paid parental leave (up to 4 weeks), and partially paid sabbatical leave (up to 6 months).--- -
    Our Commitment to DiversityWe are proud to be an Equal Employment Opportunity (EEO) and Vietnam Era Veterans Readjustment Assistance Act (VEVRAA) Employer. We are committed to cultivating a workplace in which diverse perspectives and experiences are welcomed and respected. We do not discriminate on the basis of race, color, religion, creed, ancestry, national origin, sex, age, disability (physical or mental), marital or veteran status, genetic information, sexual orientation, gender identity, political ideology, or membership in any other legally protected class. We are an Affirmative Action employer. We encourage individuals with diverse backgrounds to apply and desire priority referrals of protected veterans. If due to a disability you need assistance/and or a reasonable accommodation during the application or recruiting process, please send a request to our Employee Services Center at hrops@fredhutch.org or by calling 206-667-4700.

Keywords: Fred Hutchinson Cancer Research Center, Seattle , Transgenic Animal Core Specialist, Other , Seattle, Washington